The principal effectors of drug metabolism are the cytochrome P450 (CYP450) enzymes. The hydrophilic group (-OH) liberty caps identification has been unmasked in acetaminophen at this site. Phenacetin has also analgesic and antipyretic activity but due to hepatotoxicity toxicity, it was withdrawn from the market. But it was proved that phenacetin is converted into acetaminophen […]
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